When the Tests Disagree: The Diagnostic Gap Between Cytology and Histopathology in Canine Splenic Masses

When the Tests Disagree: The Diagnostic Gap Between Cytology and Histopathology in Canine Splenic Masses

June 23, 2026 · 16 min

About this episode

The episode discusses the discrepancies between cytology and histopathology in diagnosing canine splenic masses.

Send us Fan Mail A splenic mass shows up on ultrasound and the question hits like a brick: benign or malignant? We go straight at the uncomfortable truth behind canine splenic cytology. Even when splenic FNA feels like the “do something now” step, the match between cytology and histopathology is only moderate, and that has consequences for how we advise families, schedule rechecks, and decide when splenectomy is the safest path. We talk with Drs. Janet Grimes and Matthew Aluisio about what t...

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Guests: Dr. Janet Grimes, Dr. Matthew Aluisio

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Organizations: AVMA Journals

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