VAR Review with Dr. Bixby: Reversing the Call on MPAL

VAR Review with Dr. Bixby: Reversing the Call on MPAL

July 1, 2026 · 1h 7m · Season 1 · Episode 49

About this episode

The episode discusses the challenges in diagnosing and treating acute leukemias of mixed lineage with Dr. Bixby.

In this episode, Anthony and Bernie are joined by the great Dr. Bixby to discuss the difficulties in the diagnosis and treatment of acute leukemias of mixed or ambiguous lineage (ALAL/MPAL). We discuss: - Diagnostic uncertainties and how the criteria for diagnosis have changed over the years - Data behind the optimal treatment of MPAL and uncertainties in the literature - Promising data for the FLAG-VIPR hybrid regimen and other novel treatment strategies

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