Your Brain On... Menopause Hormone Therapy

Your Brain On... Menopause Hormone Therapy

From Your Brain On by Drs. Ayesha and Dean Sherzai

May 13, 2026 · 1h 29m · Season 7 · Episode 1

About this episode

The episode discusses the relationship between menopause hormone therapy and brain health, examining the evidence against popular claims of dementia prevention.

Menopause hormone therapy and your brain: what the evidence says vs. what the algorithm is selling you. Two-thirds of Alzheimer's patients are women. That statistic has fueled a social media narrative that hormone therapy can prevent dementia, but the current evidence doesn't support that claim. In this episode, Drs. Ayesha and Dean Sherzai sit down with OBGYN Dr. Jen Gunter and neuroscientist Dr. Sarah McKay to separate the science from the soundbites. Your Brain On... Menopause Hormone Therapy [Season 7, Episode 1] Get our FREE NEURO Plan Brain Health Playbook: https://thebraindocs.com/playbook In this episode: Why menopause hormone therapy is the gold standard for hot flashes and night sweats but not a proven tool for dementia prevention The Women's Health Initiative: what it actually found, how the press conference distorted the findings, and what we've learned since Why "bioidentical hormones" is a marketing term, not a medical one, and what that means for the products being sold to you How the hypothalamus drives vasomotor symptoms and why sleep disruption may explain much of the cognitive fog women experience at midlife The high placebo response rate with hormone therapy…

People in this episode

Hosts: Dr. Ayesha Sherzai, Dr. Dean Sherzai

Guests: Dr. Jen Gunter, Dr. Sarah McKay

Topics covered

  • menopause hormone therapy
  • Alzheimer's disease
  • dementia prevention
  • women's health
  • cognitive function
  • hormonal treatments

Keywords

  • menopause
  • hormone therapy
  • Alzheimer's
  • dementia
  • cognitive fog
  • bioidentical hormones
  • Women's Health Initiative

Mentioned in this episode

Organizations: The Women's Health Initiative

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