Enactivism, Buddhist Epistemology & the Cosmic Play with Hüseyin Beyköylü

Enactivism, Buddhist Epistemology & the Cosmic Play with Hüseyin Beyköylü

June 8, 2026 · 2h 12m

About this episode

A deep conversation with Hüseyin Beyköylü on cognitive science, epistemology, and the nature of truth.

Hüseyin Beyköylü left medicine for cognitive science after an LSD experience, and five years later he's arguing that mainstream psychology and neuroscience are built on assumptions that systematically miss what matters most about the mind. This is a dense, careful conversation about epistemology, metaphysics, and why randomized controlled trials can't capture human transformation. We get into the entropy-fluency hypothesis, how destabilization and reorganization cycle through every scale from insight to mystical experience, and why false fluency (the smoothness of a conspiracy theory, the comfort of a simplified worldview) is just as real as the real thing. In the second half, the conversation opens into metaphysics: what is truth, is there a ground, and does groundlessness mean nothing matters? Hüseyin draws on Madhyamaka, Spinoza, Karen Barad, and Varela to argue that reality is a cosmic play we actively participate in, and that truth is something you embody rather than correspond to. TIMESTAMPS 0:00:00 - Introduction & Hüseyin's Background 0:02:16 - From Medicine to Psychedelic Research: The LSD Pivot 0:05:05 - Overview of Published Papers 0:06:31 - The 4P Model: Four Ways of…

People in this episode

Host: Tiago Vasconcelos

Guest: Hüseyin Beyköylü

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Keywords

Mentioned in this episode

Books & works: Madhyamaka

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