An Existential Crisis for Alzheimer's Research?
About this episode
This episode discusses a study revealing significant molecular differences between living and post-mortem brain tissue, questioning the foundation of Alzheimer's research.
In this episode, we discuss a study published in PLOS One that compared living brain tissue to post-mortem brain tissue and found dramatic molecular differences between the two. The findings raise serious questions about decades of Alzheimer's research built on post-mortem analysis and may help explain why pharmaceutical treatments for the disease have been so disappointing Study: A Study of RNA Splicing and Protein Expression in the Living Human Brain -------------- To submit a question for us to answer on the podcast, go to brainjo.academy/question . To subscribe to the free Better Brain Fitness newsletter, join us when we record live, and get our Guide and Checklist to essential blood tests and nutrients, go to: betterbrain.fitness . To learn more about how you can boost brain fitness with neuroscience-based musical instruction, head to brainjo.academy . Intro and Outro music composed and produced by Julienne Ellen .
People in this episode
Host: Josh Turknett, MD
Topics covered
- Alzheimer's research
- brain tissue study
- molecular differences
- pharmaceutical treatments
- RNA splicing
- protein expression
Mentioned in this episode
Organizations: PLOS One
Books & works: A Study of RNA Splicing and Protein Expression in the Living Human Brain
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