Can a Blood Test Predict Alzheimer's?

Can a Blood Test Predict Alzheimer's?

April 14, 2026 · 29 min

About this episode

This episode discusses a study on a blood test that claims to predict Alzheimer's disease, examining its effectiveness and implications for testing.

A recent study published in Nature Medicine claims a blood test can predict when you'll develop Alzheimer's disease, and it got a lot of attention. But how well does it actually work, and should you rush out and get tested? In this episode, we break down the study behind the headlines to understand what it really shows, where the major limitations lie, and what it means for anyone thinking about getting this kind of test. Topics and Questions Covered What P-Tau 217 is and why it's become the leading blood-based biomarker in Alzheimer's research. How researchers built a predictive "clock" from blood test data and what that process required. The important distinction between having pathology in your brain and actually developing dementia. Who should and should not be getting tested. What a large Norwegian population study reveals about the overlap between pathology and normal cognitive function. How biomarkers like this might eventually fit into a broader, more personalized approach to prevention. and more! -------------- To submit a question for us to answer on the podcast, go to brainjo.academy/question . To subscribe to the free Better Brain Fitness newsletter, join us when we…

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Host: Josh Turknett, MD

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Organizations: Nature Medicine, brainjo.academy, betterbrain.fitness

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