The Overlooked Side of Autophagy Causing Aging - Part 2
About this episode
This episode explores the critical role of autophagy in skin health and aging, focusing on long-lived cells and their maintenance processes.
The melanocytes giving pigment to your skin right now might be older than your car. They have been sitting in your dermis for decades, and unlike the cells on your skin's surface, they do not get replaced. They have to keep themselves clean which happens through autophagy. In Part 2 of our autophagy deep dive, we get specific about how skin handles autophagy differently from other parts of the body. We unpack why long-lived cells like fibroblasts and melanocytes depend on this cleanup process, what happens when it fails, and how it ties directly to gray hair, hyperpigmentation, sagging skin, and that brownish dullness no serum seems to fix. We also introduce one of the most overlooked players in this entire conversation, and explain why we believe it is the next NAD. If you want to understand what is actually happening underneath your skin as it ages, and what tools we have to intervene at the cellular level, this episode is for you. What's Discussed: (01:06) Why skin needs autophagy more than almost any other organ (03:07) The cells on your face that may be older than your car (04:25) The 2013 paper that linked autophagy failure to dermatitis (08:44) Zombie mitochondria and why…
More episodes of Biohacking Beauty: The Anti-Aging Skincare Podcast
- The Death of Anti-Aging Skincare & The Longevity Framework That Replaces It
- The Overlooked Side of Autophagy Causing Aging - Part 1
- Chris Mirabile: Why One Ingredient Will Never Stop You From Aging (And What Actually Does)
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