Startups, philanthropy, billionaires, academia, neuromodulation, psychedelics, AI and new therapies in bipolar, autism, and Parkinson’s with Rob Malenka

Startups, philanthropy, billionaires, academia, neuromodulation, psychedelics, AI and new therapies in bipolar, autism, and Parkinson’s with Rob Malenka

From Business Trip by Greg Kubin & Matias Serebrinsky

September 23, 2025 · 1h 33m · Season 1 · Episode 68

About this episode

Matias interviews Rob Malenka about the complexities and challenges in psychiatry and the potential of new therapies.

Matias interviews Rob Malenka. In this episode, we discuss: Why progress in psychiatry is slow because the brain is the most complex organ and many disorders are highly heterogeneousThe bottlenecks including weak replicability in research, academic politics, perverse incentives, and pharma’s avoidance of neuropsychiatryHow breakthroughs require early detection, rigorous science, and bridging academia with biotech through venture philanthropyHow success depends on mission-driven, ethical peopl...

People in this episode

Host: Matias Serebrinsky

Guest: Rob Malenka

Topics covered

  • psychiatry
  • neuromodulation
  • psychedelics
  • bipolar disorder
  • autism
  • Parkinson's disease
  • venture philanthropy

Keywords

  • psychiatry
  • neuromodulation
  • psychedelics
  • bipolar
  • autism
  • Parkinson's
  • venture philanthropy
  • research bottlenecks
  • academic politics
  • neuropsychiatry

Mentioned in this episode

Organizations: pharma, biotech, psychiatry, venture philanthropy

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