
157: The Controversial History of Hormone Therapy: How Fear Shaped Women's Health
From Confessions of a Male Gynecologist by Shawn Tassone MD PhD
January 8, 2026 · 40 min · Episode 157
About this episode
Dr. Shawn Tassone explores the controversial history of hormone replacement therapy and its impact on women's health.
Hormone replacement therapy (HRT) has become one of the most misunderstood, and controversial, topics in women's health. In this episode, Dr. Shawn Tassone takes a deep dive into how we got here and why so much of what women have been told about hormones simply doesn't hold up. Dr. Tassone unpacks the complicated history of HRT, including the lasting fallout from the Women's Health Initiative study and how its misinterpretation shaped decades of fear-based medical decision-making. He addresses persistent myths linking estrogen to breast cancer, challenges outdated assumptions, and explains why hormones were never the villain they were made out to be. This conversation goes beyond the science. Dr. Tassone also critiques the modern hormone industry, calling out profit-driven practices, poor education, and the ongoing failure of the medical system to prioritize women's long-term health. At its core, this episode is a call for clarity, context, and compassion — because women deserve better than fear, confusion, and half-truths when it comes to their bodies. Episode Highlights: Why hormones remain one of the most misunderstood topics in medicine How the Women's Health Initiative study…
People in this episode
Host: Shawn Tassone
Topics covered
- hormone therapy
- women's health
- medical history
- estrogen
- HRT misconceptions
- healthcare practices
Keywords
- hormone replacement therapy
- HRT
- women's health
- estrogen
- Women's Health Initiative
- medical decision-making
- breast cancer
- healthcare
- myths
Mentioned in this episode
Organizations: Women's Health Initiative
Products: hormone replacement therapy, HRT, estrogen
Places: women
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