Redefining Non-Small Cell Lung Cancer Care: Updates in Targeted and Perioperative Therapy
From Deep Breaths: Updates from CHEST by ReachMD
December 22, 2025 · 17 min
About this episode
The episode discusses significant updates in non-small cell lung cancer care from recent conferences, focusing on targeted therapies and perioperative strategies.
Guest: Gerard A. Silvestri MD, MS, Master FCCP Guest: Mariam Alexander, MD, PhD Guest: Jessica S. Donington, MD, MSCR The 2025 European Society for Medical Oncology Congress and World Conference on Lung Cancer revealed significant updates in non-small cell lung cancer care. Learn more as Drs. Gerard Silvestri, Mariam Alexander, and Jessica Donington review new data on EGFR- and ROS1-targeted therapies, perioperative immunotherapy, and multidisciplinary strategies to expand resectability in stage III non-small cell lung cancer. Dr. Silvestri is a pulmonologist and the Hillenbrand Professor of Thoracic Oncology at the Medical University of South Carolina. Dr. Alexander is an Assistant Professor of Medical Oncology at the Medical University of South Carolina. Dr. Donington is a Professor in Surgery and Chief of the Section of Thoracic Surgery at the University of Chicago. This program is produced in partnership with the American College of Chest Physicians and is sponsored by AstraZeneca.
People in this episode
Hosts: Gerard A. Silvestri, Mariam Alexander, Gerard Silvestri
Guests: Gerard A Silvestri Md Ms Master Fccp, Mariam Alexander Md Phd, Jessica S Donington Md Mscr
Topics covered
- non-small cell lung cancer
- targeted therapy
- perioperative therapy
- immunotherapy
- multidisciplinary strategies
Keywords
- EGFR
- ROS1
- resectability
- stage III lung cancer
Sponsors
AstraZeneca
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