What Type 2 Inflammation in COPD Means for Treatment Decision Making

What Type 2 Inflammation in COPD Means for Treatment Decision Making

From Deep Breaths: Updates from CHEST by ReachMD

March 6, 2026 · 15 min

About this episode

Drs. Christenson and Maselli discuss the impact of type 2 inflammation on treatment decisions in COPD.

Host: Stephanie Christenson, MD Guest: Diego Maselli, MD, FCCP COPD is increasingly recognized as a heterogeneous disease, and for a subset of patients, type 2 inflammation plays a meaningful role in exacerbation risk and treatment response. Given that, Drs. Stephanie Christenson and Diego Maselli come together to examine how insights into the pathobiology of type 2 inflammation can directly inform clinical decision making in COPD. Specifically, they discuss the practical use of blood eosinophil counts to phenotype patients, assess risk, and guide therapy selection within the context of GOLD 2025 and 2026 guidance. Dr. Christenson is an Associate Professor at the University of California San Francisco in the Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, and Dr. Maselli is a Professor of Medicine at the Long School of Medicine at UT Health in San Antonio. This episode of Deep Breaths: Updates from CHEST was supported by a non-promotional, non-CME educational program brought to you by CHEST in collaboration with and sponsored by GSK.

People in this episode

Guest: Diego Maselli Md Fccp

Topics covered

  • COPD
  • type 2 inflammation
  • treatment decision making
  • blood eosinophil counts

Keywords

  • exacerbation risk
  • treatment response
  • clinical decision making
  • GOLD 2025
  • GOLD 2026

Sponsors

GSK

Mentioned in this episode

Books & works: Deep Breaths: Updates from CHEST

Places: San Antonio

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