Do GLP-1 Medicines Actually Cause Muscle Loss? New Research With Dr. Henning Langer

Do GLP-1 Medicines Actually Cause Muscle Loss? New Research With Dr. Henning Langer

April 14, 2026 · 36 min · Episode 149

About this episode

The episode discusses the effects of GLP-1 medicines on muscle loss with insights from Dr. Henning Langer's research.

Dr. Spencer Nadolsky and Karl sit down with Dr. Henning Langer, a PhD researcher at the Charité in Berlin, to break down his newly published paper combining rodent and human data to look directly at what GLP-1 medicines actually do to skeletal muscle beyond what a DEXA scan can tell you. From mice running to exhaustion on semaglutide to maximum voluntary contraction data in humans, this is the most granular conversation yet on whether these drugs are doing something to muscle that nobody fully understands yet.

People in this episode

Hosts: Dr. Spencer Nadolsky, Karl

Guest: Dr. Henning Langer

Topics covered

Keywords

Mentioned in this episode

Organizations: Charité

Products: GLP-1 medicines, semaglutide

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