GLP-1 Genetics: Predicting Weight Loss and Side Effects With 23andMe's Dr. Adam Auton

GLP-1 Genetics: Predicting Weight Loss and Side Effects With 23andMe's Dr. Adam Auton

From Docs Who Lift by Docs Who Lift

April 21, 2026 · 25 min · Episode 150

About this episode

Dr. Spencer Nadolsky and Karl discuss genetic factors influencing weight loss and side effects of GLP-1 medications with Dr. Adam Auton from 23andMe.

Dr. Spencer Nadolsky and Karl sit down with Dr. Adam Auton, geneticist at 23andMe, to break down a brand new paper using data from over 27,000 people that identified specific genetic variants in the GLP-1 receptor and GIP receptor that predict both how much weight someone loses on these medications and how likely they are to experience side effects. This is one of the first studies to show that precision medicine for GLP-1 drugs may already be closer than most people think.

People in this episode

Hosts: Dr. Spencer Nadolsky, Karl

Guest: Dr. Adam Auton

Topics covered

  • genetics
  • weight loss
  • GLP-1 drugs
  • precision medicine
  • side effects
  • healthcare

Keywords

  • GLP-1
  • genetics
  • weight loss
  • side effects
  • 23andMe
  • precision medicine
  • health

Mentioned in this episode

Organizations: 23andMe

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