The Alzheimer's Drugs Don't Work — Here's What Does (featuring Dr. David Perlmutter) | EP 416

The Alzheimer's Drugs Don't Work — Here's What Does (featuring Dr. David Perlmutter) | EP 416

August 18, 2026 · 1h 16m · Episode 416

About this episode

Dr. David Perlmutter discusses the ineffectiveness of Alzheimer's drugs and the importance of microglia in brain health.

Big Pharma bet billions on one theory: clear the amyloid, cure Alzheimer's. A new Cochrane review of 20,000+ patients just proved them wrong — these drugs don't work, and they may be putting your brain at risk. So what's really driving this epidemic? My guest today, six-time New York Times bestselling author and board-certified neurologist Dr. David Perlmutter, says the answer lies in a set of cells most people have never even heard of — and he lays it all out in his new book, Brain Defenders . The good news is, you already have more control over them than any drug could ever give you. We're talking about microglia, the brain's immune cells, and why the choices you make today may matter more than anything a prescription pad can offer. For full show notes and transcript: https://drgundry.com/david-perlmutter-alzheimers On this episode, you’ll learn:   All about the new study that found leading Alzheimer's drugs deliver almost no benefit (02:09) Why the so-called enemy in your brain is not what we thought at all (07:34) What microglia are, and why these overlooked immune cells may be the real gatekeepers of your brain's health (05:15) How everyday metabolic issues like…

People in this episode

Host: Dr. Gundry

Guest: Dr. David Perlmutter

Topics covered

Keywords

Mentioned in this episode

Organizations: Big Pharma

Books & works: Brain Defenders

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