Where to Inject for MAXIMUM GLP-1 Weight Loss | What the Data Shows
About this episode
Dr. Paika discusses the impact of injection sites on GLP-1 weight loss therapy based on pharmacokinetic study data.
#GLP1 #Ozempic #Zepbound #WeightLossJourney #ObesityMedicine Injecting your GLP-1 in the same spot every week and wondering if another site would work better? I break down the actual Eli Lilly pharmacokinetic study comparing abdomen, thigh, and upper arm injections for tirzepatide (Mounjaro/Zepbound) — what the data really shows about absorption, side effects, and appetite suppression, and where the study's small sample size means the "abdomen wins" headline deserves a second look. By the end, you'll know exactly how much injection site affects your results — and where to actually focus if you want long-term success on GLP-1 therapy. Learn the full framework I use with my own patients — nutrition, training, and troubleshooting your treatment — inside my GLP-1 Masterclass: https://drmohammedpaika.com Timestamps 0:00 Cold Open 0:57 Meet Dr. Paika 1:38 The 3 Questions This Video Answers 2:50 How GLP-1 & GIP Actually Work 4:57 The 3 FDA-Approved Injection Sites 6:18 Why This Study Matters 7:58 Inside the Study: Design & Methodology 9:06 The Half-Life Detour (Why 35 Days) 10:27 Finding #1: Total Drug Absorbed (AUC) 12:55 Finding #2: Peak Concentration (Cmax) 14:16 Finding #3…
Topics covered
- GLP-1 therapy
- weight loss
- injection sites
- pharmacokinetics
- obesity medicine
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