Ep 213 Update in Management of Status Epilepticus

Ep 213 Update in Management of Status Epilepticus

From Emergency Medicine Cases by Dr. Anton Helman

February 10, 2026 · 59 min

About this episode

This episode discusses the management of convulsive status epilepticus in the emergency department, emphasizing the importance of timely intervention.

Convulsive status epilepticus is one of the most morbid neurologic emergencies we manage in the ED, and outcomes depend far more on speed than drug selection. Like ventricular fibrillation, each minute of ongoing convulsions worsens hypoxia, acidosis, cardiovascular instability, and neuronal injury, while making seizures progressively harder to terminate. Modern definitions are intentionally time-compressed to force early, parallel, clock-anchored action. Any patient still convulsing when you reach the bedside should be treated as evolving status epilepticus. In this EM Cases podcast with Dr. Sara Gray, we take a practical, time-based approach to convulsive status epilepticus, focusing on early, adequately dosed benzodiazepines, avoiding common escalation and dosing pitfalls, anticipating post-ictal cardiovascular collapse, and knowing when to escalate to second-line agents, airway control, and anesthetic-dose therapy. We also address the transition to non-convulsive status epilepticus and how to recognize ongoing seizures when EEG is not immediately available. We answer questions such as: Why does time to first benzodiazepine matter more than the drug or route? What critical…

People in this episode

Host: Dr. Anton Helman

Guest: Dr. Sara Gray

Topics covered

  • status epilepticus
  • emergency medicine
  • neurologic emergencies
  • benzodiazepines
  • seizure management

Keywords

  • status epilepticus
  • emergency department
  • benzodiazepines
  • seizure management
  • neurological emergencies

Mentioned in this episode

Organizations: Emergency Medicine Cases

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