New Hope for ME/CFS and Long COVID Patients
About this episode
Haylie Pomroy interviews Dr. David Systrom about exercise intolerance in ME/CFS and long COVID, discussing the underlying science and ongoing clinical trials.
In today's episode, Haylie Pomroy sits down with Dr. David Systrom, a pulmonary and critical care physician at Mass General Brigham and Assistant Professor at Harvard Medical School, to explore the science behind exercise intolerance in ME/CFS and long COVID. Dr. Systrom breaks down the invasive cardiopulmonary exercise test (CPET) and what it reveals about blood flow, oxygen extraction, and mitochondrial dysfunction in patients who have been told their tests are normal. He explains why dysautonomia, small fiber neuropathy, and acquired mitochondrial dysfunction may be driving the fatigue, post-exertional malaise, and wide-ranging symptoms these patients experience every day. He also shares details on two active clinical trials at Brigham and Women's Hospital, including the LYFT trial testing low-dose naltrexone, Pyridostigmine (Mestinon), and the combination of both, as well as a muscle biopsy study designed to understand the role of the mitochondrion in post-exertional malaise. If you or someone you love has been dismissed, misdiagnosed, or left without answers, tune in to Fast Metabolism Matters Dr. David Systrom is a physician at Brigham and Women's Hospital. He is also an…
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