Season 6 Episode 6: Operationalizing the Shift

About this episode

This episode discusses translating innovative nephrology research ideas into practical trial strategies.

Building on the concepts introduced in the previous episode Rethinking the Design and Conduct of Kidney Trials , this episode explores how innovative ideas in nephrology research can be translated into practical trial strategies. Experts discuss novel approaches to trial design, evolving endpoint selection, and the importance of engaging patients, clinicians, regulators, and other stakeholders throughout the research process. Drawing on insights from the ISN Consensus Meeting on Changing Paradigms of Studies in CKD (Vancouver, Nov 22-23, 2024) , the discussion highlights how more pragmatic and implementation-focused trials can help generate evidence that is meaningful for clinical practice and patient care worldwide. Speakers Adeera Levin Professor of Medicine, University of British Columbia, Canada, and Past-President of the International Society of Nephrology (ISN). Dr. Levin is a global leader in kidney health research, with extensive experience in chronic kidney disease (CKD) management, clinical trials, and international health system strengthening. David Wheeler Professor of Kidney Medicine at University College London, UK and Honorary Consultant Nephrologist at the Royal…

People in this episode

Hosts: Roberto Pecoits-Filho, Smeeta Sinha

Guests: Adeera Levin, David Wheeler

Topics covered

• nephrology research
• trial design
• chronic kidney disease
• patient engagement
• clinical practice
• implementation-focused trials

Keywords

• kidney trials
• nephrology
• clinical trials
• patient care
• evidence generation

Mentioned in this episode

Organizations: University of British Columbia, International Society of Nephrology, University College London, Royal Free Hospital

More episodes of Global Kidney Care Podcast Provided by ISN

• Season 6 Episode 5: The Global Shortage of Nephrology Nurses · April 30, 2026 · 50 min
• Season 6 Episode 4: Tackling One of Nephrology’s Biggest Mysteries: chronic kidney disease of unknown origin (CKDu) · April 24, 2026 · 48 min
• Season 6 Episode 3: The Emerging Role of Artificial Intelligence in Nephrology · March 10, 2026 · 52 min
• Season 6 Episode 2: WKD: Kidney Health for All: Caring for People, Protecting the Planet · February 4, 2026 · 36 min
• Season 6 Episode 1: Genetics for the Nephrologist (a sneak peek at the Genetics in Kidney Disease Curriculum) · January 13, 2026 · 54 min
• Season 5 Episode 10: AI and Acute Kidney Injury Detection · December 3, 2025 · 47 min