
AI-Powered Longevity Science — One Gene to Reverse Aging? | Daniel Ives PhD
From Health Longevity Secrets by Robert Lufkin MD
April 28, 2026 · 1h 26m · Episode 259
About this episode
Dr. Daniel Ives discusses the discovery of a gene that may reverse aging using AI technology.
What if an AI could run centuries of aging experiments in a year? Dr. Daniel Ives, CEO of Shift Bioscience, explains how his team used a virtual cell to discover SB000 — a single gene that matches Yamanaka factor rejuvenation without cancer risk. CHAPTERS: 00:00 — Centuries of experiments in a year 02:03 — Daniel's journey: physics → Aubrey de Grey 10:08 — The epigenetic clock breakthrough 12:09 — The 13 mitochondrial genes 20:09 — Yamanaka factors (OSKM) explained 22:10 — Partial reprogramm...
People in this episode
Host: Robert Lufkin MD
Guest: Daniel Ives
Topics covered
- AI in longevity
- gene therapy
- aging research
- epigenetics
- mitochondrial genes
Keywords
- AI
- longevity
- aging
- SB000
- Yamanaka factors
- epigenetic clock
- mitochondrial genes
Mentioned in this episode
Organizations: Shift Bioscience
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