EXPLAINER: Medicine's Forgotten Biomarker - The Homocysteine Story Your Doctor Missed

About this episode

This episode discusses the discovery and implications of homocysteine as a biomarker for heart disease, highlighting its historical suppression in the medical community.

In 1969, Harvard pathologist Kilmer McCully discovered elevated homocysteine causes arterial damage and heart disease. He was forced out of Harvard. The Framingham Heart Study confirmed him. Then the AHA buried it anyway. CHAPTERS: 00:00 - McCully discovery and suppression 01:20 - Part 1: What homocysteine does to arteries (6 mechanisms) 03:25 - Part 2: The evidence they ignored 03:40 - Every 5 umol/L: 20-30% higher CAD risk, 60% stroke risk 04:50 - Alzheimers risk +48% (meta-analysis, 7,474...

People in this episode

Host: Robert Lufkin MD

Topics covered

• homocysteine
• heart disease
• arterial damage
• medical history
• biomarkers

Keywords

• homocysteine
• heart disease
• arterial damage
• Alzheimer's risk
• Framingham Heart Study

Mentioned in this episode

Organizations: Harvard, AHA, Framingham Heart Study

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