Creatine, Cellular Energy, and the Modern Stress Epidemic | HOMe Podcast #010

Creatine, Cellular Energy, and the Modern Stress Epidemic | HOMe Podcast #010

May 13, 2026 · 26 min · Season 2 · Episode 10

About this episode

The episode explores the science and clinical application of creatine beyond its performance supplement reputation.

In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the science and clinical application of creatine. Moving beyond its reputation as just a performance supplement for "gym bros," Boomer Anderson, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Ted Achacoso break down how creatine functions as a critical cellular battery buffer. Join us as we delve into: How creatine bypasses the "methylation tax" by saving the body from depleting SAMe reserves to produce energy. Why muscle is a metabolic determinant of resilience and not just a cosmetic feature. The evolutionary mismatch that increases our cellular energy demands due to a highly sympathetic, stressed lifestyle. The role of creatine in brain health is particularly important for supporting working memory, mitigating cognitive fatigue, and protecting against excitotoxicity. This episode is for you if: You are curious about how to support your body's cellular energy and mitochondrial function. You follow a vegetarian or plant-based diet and want to understand your specific creatine supplementation needs. You want to understand the difference between…

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