46. High Homocysteine: Histamine, Methylation & Why You Might Not Tolerate Methylated B Vitamins

46. High Homocysteine: Histamine, Methylation & Why You Might Not Tolerate Methylated B Vitamins

From Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health by Joanne Kennedy

May 4, 2026 · 12 min

About this episode

Joanne discusses the relationship between high homocysteine levels, histamine intolerance, and the effects of methylated B vitamins on health.

Can methylated B vitamins make your symptoms worse instead of better? In this episode of The Histamine Well Podcast, Joanne explains the connection between high homocysteine, histamine intolerance, methylation, and why some people react poorly to methylated nutrients. High homocysteine is associated with cardiovascular disease, cognitive decline, inflammation, and neurological health concerns — yet lowering it isn’t always simple. Many people experience headaches, anxiety, insomnia, digestive...

People in this episode

Host: Joanne Kennedy

Topics covered

  • high homocysteine
  • histamine intolerance
  • methylation
  • methylated B vitamins
  • cardiovascular health
  • cognitive health

Keywords

  • high homocysteine
  • histamine intolerance
  • methylation
  • methylated B vitamins
  • cardiovascular disease
  • cognitive decline
  • inflammation
  • neurological health

Mentioned in this episode

Organizations: cardiovascular disease, cognitive decline, inflammation, neurological health concerns

Products: methylated B vitamins, methylated nutrients, high homocysteine

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