
46. High Homocysteine: Histamine, Methylation & Why You Might Not Tolerate Methylated B Vitamins
From Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health by Joanne Kennedy
May 4, 2026 · 12 min
About this episode
Joanne discusses the relationship between high homocysteine levels, histamine intolerance, and the effects of methylated B vitamins on health.
Can methylated B vitamins make your symptoms worse instead of better? In this episode of The Histamine Well Podcast, Joanne explains the connection between high homocysteine, histamine intolerance, methylation, and why some people react poorly to methylated nutrients. High homocysteine is associated with cardiovascular disease, cognitive decline, inflammation, and neurological health concerns — yet lowering it isn’t always simple. Many people experience headaches, anxiety, insomnia, digestive...
People in this episode
Host: Joanne Kennedy
Topics covered
- high homocysteine
- histamine intolerance
- methylation
- methylated B vitamins
- cardiovascular health
- cognitive health
Keywords
- high homocysteine
- histamine intolerance
- methylation
- methylated B vitamins
- cardiovascular disease
- cognitive decline
- inflammation
- neurological health
Mentioned in this episode
Organizations: cardiovascular disease, cognitive decline, inflammation, neurological health concerns
Products: methylated B vitamins, methylated nutrients, high homocysteine
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