Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health
by Joanne Kennedy
Is this your podcast?Insights from recent episode analysis
Audience Interest
Podcast Focus
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Platform Reach
Insights are generated by CastFox AI using publicly available data, episode content, and proprietary models.
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Total monthly reach
Estimated from 11 chart positions in 11 markets.
By chart position
- 🇦🇺AU · Alternative Health#5230K to 100K
- 🇨🇦CA · Alternative Health#10030K to 100K
- 🇺🇸US · Alternative Health#1645K to 30K
- 🇧🇷BR · Alternative Health#4730K to 100K
- 🇳🇱NL · Alternative Health#1311K to 10K
- Per-Episode Audience
Est. listeners per new episode within ~30 days
44K to 148K🎙 Daily cadence·53 episodes·Last published 2d ago - Monthly Reach
Unique listeners across all episodes (30 days)
147K to 493K🇦🇺20%🇨🇦20%🇧🇷20%+8 more - Active Followers
Loyal subscribers who consistently listen
59K to 197K
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Platform Distribution
Reach across major podcast platforms, updated hourly
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* Data sourced directly from platform APIs and aggregated hourly across all major podcast directories.
On the show
From 15 epsHost
Recent guests
No guests detected in recent episodes.
Recent episodes
51. Methylation Optimisation: What The Biohacking Trend Gets Wrong
Jun 22, 2026
11m 50s
50. Is PMDD a Histamine Problem? H1 and H2 Blockers Explained
Jun 15, 2026
23m 01s
49. Mould & Mitochondria: Why You're Still Exhausted (and What's Really Driving It)
Jun 8, 2026
11m 53s
48. How Mould Mycotoxins Cause SIBO
Jun 1, 2026
15m 05s
47. The Bile-Histamine Connection: SIBO, Estrogen, Mold & Oxalates Explained
May 25, 2026
10m 31s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 6/22/26 | 51. Methylation Optimisation: What The Biohacking Trend Gets Wrong | Methylation has become one of the hottest topics in functional medicine, biohacking, and wellness. From MTHFR testing to methylated supplements, many people are being told that boosting methylation is the key to better energy, mood, detoxification, hormone balance, and longevity. But what if more methylation isn't always better? In this episode, Joanne explores the science behind methylation, the roles of MTHFR and COMT, and why relying solely on genetic reports can lead to inappropriate supp... | 11m 50s | ||||||
| 6/15/26 | 50. Is PMDD a Histamine Problem? H1 and H2 Blockers Explained | Could histamine be contributing to Premenstrual Dysphoric Disorder (PMDD)? In this episode of The Histamine Well Podcast, Joanne explores the growing interest in the connection between PMDD, histamine intolerance, mast cell activation, and hormonal fluctuations. As more women report improvements in PMDD symptoms with antihistamines, the question is gaining attention: could histamine be a missing piece of the PMDD puzzle? Joanne breaks down the science behind the estrogen-histamine feedback lo... | 23m 01s | ||||||
| 6/8/26 | 49. Mould & Mitochondria: Why You're Still Exhausted (and What's Really Driving It)✨ | mould illnessmitochondrial dysfunction+3 | — | Histamine Well Podcast | mouldmitochondria | mould illnessmitochondrial dysfunction+3 | — | 11m 53s | |
| 6/1/26 | 48. How Mould Mycotoxins Cause SIBO✨ | mould mycotoxinsSIBO+3 | — | Histamine Well PodcastSIBO+1 | — | mouldmycotoxins+5 | — | 15m 05s | |
| 5/25/26 | 47. The Bile-Histamine Connection: SIBO, Estrogen, Mold & Oxalates Explained✨ | bile flowhistamine intolerance+5 | — | SIBOEstrogen+4 | — | histamine symptomsbile flow+6 | — | 10m 31s | |
| 5/4/26 | 46. High Homocysteine: Histamine, Methylation & Why You Might Not Tolerate Methylated B Vitamins✨ | high homocysteinehistamine intolerance+4 | — | methylated B vitaminsmethylated nutrients+5 | — | high homocysteinehistamine intolerance+6 | — | 12m 29s | |
| 4/29/26 | Q&A. Should I Take Calcium-D-Glucarate Whilst On HRT Oestrogen?✨ | Calcium-D-GlucarateHRT+4 | — | Calcium-D-GlucarateHRT+4 | — | Calcium-D-GlucarateHRT+5 | — | 4m 31s | |
| 4/27/26 | 45. Case Study: SIBO, Histamine Intolerance & Hormonal Imbalance✨ | SIBOhistamine intolerance+3 | — | SIBOPMS+1 | — | SIBOhistamine intolerance+6 | — | 16m 54s | |
| 4/22/26 | Q&A. How Do Epsom Salt Baths Work & Why Are They Good For Me?✨ | Epsom salt bathsdetoxification+5 | — | Epsom saltmagnesium sulfate | — | Epsom saltdetoxification+6 | — | 4m 35s | |
| 4/20/26 | 44. Sulfur Intolerace Explained: What Is It? Why Does It Happen? How Does It Increase Histamine?✨ | sulfur intolerancehistamine intolerance+3 | — | broccoligarlic+2 | — | sulfur intolerancehistamine+5 | — | 24m 01s | |
Want analysis for the episodes below?Free for Pro Submit a request, we'll have your selected episodes analyzed within an hour. Free, at no cost to you, for Pro users. | |||||||||
| 4/15/26 | Q&A. Why Does My Anxiety Get Worse at Night or Wake Me Up at 3am?✨ | anxietynight-time anxiety+4 | — | — | — | anxietynight anxiety+5 | — | 3m 12s | |
| 4/13/26 | 43. Blood Sugar & Anxiety in Women: The Hidden Cause of Chronic Anxiety✨ | blood sugaranxiety+3 | — | Histamine Well Podcast | — | blood sugaranxiety+5 | — | 15m 39s | |
| 4/8/26 | Q&A. Why Do I Still Have Inflammation When My CRP & ESR Are Normal?✨ | inflammationCRP+5 | — | — | — | inflammationCRP+7 | — | 3m 23s | |
| 4/6/26 | 42. Why Your Hormones Haven't Improved Despite Treatment - The Role of Inflammation, Histamine & Methylation✨ | hormonal healthinflammation+5 | — | — | — | hormonestreatment+8 | — | 13m 49s | |
| 4/1/26 | Q&A. Are Bioidentical Hormones Actually Natural?✨ | bioidentical hormoneswomen's health+3 | — | bioidentical hormonessynthetic hormones+1 | — | bioidentical hormonesnatural hormones+4 | — | 3m 00s | |
| 3/30/26 | 41. Can’t Tolerate HRT? The Hidden Reason Most Women Miss✨ | histamine intolerancehormone replacement therapy+5 | — | HRTSIBO+5 | — | histamine intoleranceHRT+8 | — | 12m 03s | |
| 3/25/26 | Q&A. How Does Sulforaphane Work in the Body? Hint: It Switches On Your Protective Genes✨ | sulforaphaneNRF2 pathway+4 | — | sulforaphaneNRF2 pathway | — | sulforaphaneNRF2+4 | — | 3m 51s | |
| 3/23/26 | 40. The GEMM Protocol: A Deeper Approach To Why Your Gut Isn't Healing - And What To Do About It | In this episode of The Histamine Well Podcast, Joanne speaks with nutritional biochemist Dr. Christine Houghton about the GEMM Protocol (Gut Ecology & Metabolic Modulation) — a science-based approach to restoring gut health by repairing the gut lining and activating protective genes. Learn how sulforaphane, NRF2 activation, and targeted microbiome support can help improve gut inflammation, histamine intolerance, food sensitivities, and chronic illness. In this episode, you’ll learn: W... | 51m 51s | ||||||
| 3/18/26 | Q&A. Should I Take Antibiotics for SIBO? | In this Q&A Clarity Session of The Histamine Well Podcast, Joanne answers a common and often confusing question: Should I take antibiotics for SIBO? The truth is—it depends. In this episode, Joanne breaks down the two distinct patient scenarios she commonly sees in clinical practice. She explains when antibiotics may be a practical and supportive option, especially for those with lifestyle limitations, and when a deeper, more comprehensive approach may be necessary to address the root c... | 5m 09s | ||||||
| 3/16/26 | 39. Why Does Your SIBO Keep Coming Back? (And What Most Treatments Miss) | Is SIBO (Small Intestinal Bacterial Overgrowth) really the root cause of your bloating and food intolerances — or is it a downstream effect of deeper dysfunction? In this episode of The Histamine Well Podcast, Joanne explains why SIBO rarely develops in isolation and why antibiotics or herbal antimicrobials alone often fail to prevent relapse. If you’ve been stuck in the cycle of treating SIBO repeatedly without lasting improvement, this episode explores the underlying mechanisms that may be ... | 13m 50s | ||||||
| 3/11/26 | Q&A. How Is Methylation Connected to Mental Health? | In this Q&A episode, we explore how methylation affects mental health, including its impact on neurotransmitters like dopamine, serotonin, and norepinephrine. Learn how the methylation cycle regulates gene expression, hormone balance, histamine clearance, and stress resilience — and why low folate, vitamin B12, B6, and B2 can contribute to symptoms such as anxiety, depression, brain fog, fatigue, insomnia, and “wired but tired” patterns. We also discuss slow COMT activity, the link betwee... | 6m 07s | ||||||
| 3/9/26 | 38. Helicobacter pylori, Low Stomach Acid & Histamine: The Gut Cascade Explained | In this episode of The Histamine Well Podcast, Joanne explains how Helicobacter pylori (H. pylori) can quietly drive histamine intolerance, SIBO, and hormone imbalance — even without classic ulcer or reflux symptoms. H. pylori produces urease, converting urea into ammonia and lowering stomach acid. This reduction in hydrochloric acid can impair protein digestion, weaken pathogen control, and disrupt digestive signaling — creating the perfect environment for small intestinal bacterial overgrow... | 13m 42s | ||||||
| 3/4/26 | Q&A. What Type of Magnesium Should I Take? | In this short Clarity Session Q&A, Joanne explains the key differences between common magnesium forms and how to choose the right one for symptoms like anxiety, sleep issues, constipation, migraines, fatigue, muscle pain, or brain fog. Learn when each type may help—and when to avoid certain forms if you’re sensitive. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your st... | 7m 17s | ||||||
| 3/2/26 | 37. Candida and Histamine: Why Fungal Overgrowth Keeps Coming Back | In this episode of The Histamine Well Podcast, Joanne explores how candida, yeast, and fungal overgrowth can worsen histamine intolerance and trigger ongoing mast cell symptoms. She explains how fungal-driven gut inflammation increases histamine production by activating mast cells, upregulating histidine decarboxylase (HDC), and reducing DAO enzyme activity — making it harder for the body to break histamine down. You’ll learn why antifungals alone often fail, how gut “terrain” factors like lo... | 14m 12s | ||||||
| 2/25/26 | Q&A. Should I Be Taking Antihistamines Long Term? | In this short Clarity Session Q&A bonus episode of The Histamine Well Podcast, Joanne explains what antihistamines actually do, why symptoms often return when you stop them, and the common root causes behind histamine issues. Learn the difference between symptom suppression and true regulation of the gut, detox pathways, and nervous system. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Hista... | 4m 23s | ||||||
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Chart Positions
11 placements across 11 markets.
Chart Positions
11 placements across 11 markets.