Physician VC Dr. John Dayton on What It Takes to Actually Build a Winning Healthcare Startup

Physician VC Dr. John Dayton on What It Takes to Actually Build a Winning Healthcare Startup

May 14, 2026 · 38 min · Season 1 · Episode 79

About this episode

Dr. John Dayton discusses the essentials of building a successful healthcare startup and the advantages of physician founders.

Dr. John Dayton is an emergency physician, Stanford innovation fellow, and co-founder of Wildfire Partners , a new healthcare seed fund built around a simple but data-backed conviction: physicians make better health tech founders than the industry has ever given them credit for. The data is hard to ignore: more than a quarter of billion-dollar healthcare companies built in the last decade had at least one clinician co-founder. John did not just write that paper. He built a fund around it. In this episode of How I Doctor, Dr. Graham Walker sits down with John to dig into what it actually takes to build a health tech company worth funding. They walk through John's Seven Ps framework for evaluating startups, what makes a pitch compelling versus an instant red flag, and why the barrier to entry for physician-founders has never been lower thanks to AI. What You'll Learn in This Episode: The Seven Ps framework John uses to evaluate every health tech company he considers funding What kills a pitch immediately and what signals a founder has actually done their homework Why AI has dramatically lowered the barrier to entry for physician-founders and what that changes about building a…

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Host: Dr. Graham Walker

Guest: Dr. John Dayton

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Organizations: Wildfire Partners, Stanford

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