Neuroscience in Hyperspace with Andrew Gallimore
From Humans On The Loop by Michael Garfield
March 25, 2026 · 1h 35m · Season 2 · Episode 33
About this episode
This episode features Andrew Gallimore discussing the implications of DMT research on consciousness and reality.
In this episode we join pioneering psychedelic neuroscientist Andrew Gallimore ( Website | X | Instagram | Substack ) to probe the bewildering high-dimensional horizons of DMT research and their implications for our understanding of consciousness and the structure of reality. In his book Death by Astonishment , Gallimore argues DMT expands the brain’s “representational reach,” enabling perception of high-dimensional structures and apparent interaction with non-human “intelligent agents,” challenging standard accounts that treat the experience as mere hallucination, dreams, or Jungian archetypes. What new shapes will we—and our sciences—take as we integrate the intense strangeness of these experiences? How do we even begin to practice “truly psychedelic” science? And what insights might we be able to bring “home” to the Flatland where we spend most of our waking lives? Andrew has talked about this work in many, many other venues (his conversations with Jesse Michels and Danny Jones were especially good), so I wanted to carry the conversation into fresh terrain. Consider this episode the “200 level course”, or at least my best attempt ask a brilliant and provocative researcher some…
People in this episode
Host: Michael Garfield
Guest: Andrew Gallimore
Topics covered
- neuroscience
- DMT research
- consciousness
- psychedelic experience
- high-dimensional structures
Keywords
- DMT
- neuroscience
- psychedelics
- consciousness
- high-dimensional
- intelligent agents
- neuroimaging
Mentioned in this episode
Books & works: Death by Astonishment
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