About this episode

The episode discusses the role of elamipretide in mitochondrial trifunctional protein deficiency and its potential in cardiolipin remodeling.

We talk with Eduardo Vieira Neto about elamipretide in mitochondrial trifunctional protein deficiency and the emerging role of cardiolipin remodeling beyond classic fatty-acid oxidation. Could this offer an add-on approach for complications that triheptanoin doesn’t fully address? Elamipretide Improves Mitochondrial Function in Mitochondrial Trifunctional Protein-Deficient Mice and Human Fibroblasts Eduardo Vieira Neto, et al https://doi.org/10.1002/jimd.70132

People in this episode

Guest: Eduardo Vieira Neto

Topics covered

• mitochondrial trifunctional protein deficiency
• cardiolipin remodeling
• elamipretide
• fatty-acid oxidation
• mitochondrial function

Keywords

• elamipretide
• triheptanoin
• mitochondrial function
• cardiolipin remodeling
• fatty-acid oxidation

Mentioned in this episode

Organizations: Journal of Inherited Metabolic Disease

Products: elamipretide, triheptanoin

Books & works: Elamipretide Improves Mitochondrial Function in Mitochondrial Trifunctional Protein-Deficient Mice and Human Fibroblasts

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