D-Glyceric aciduria: is GLYCTK really mitochondrial?

About this episode

Jörn Oliver Sass discusses the implications of D-glyceric aciduria and the role of GLYCTK in mitochondrial function.

A rare disorder, a surprisingly basic biological question, and a paper that revisits what GLYCTK actually does. Jörn Oliver Sass joins the podcast to discuss D-glyceric aciduria, mitochondrial localization of D-glycerate kinase, and why getting the fundamentals right still matters. Human D-Glycerate Kinase, Encoded by GLYCTK and Deficient in D-Glyceric Aciduria, Is a Mitochondrial Enzyme Anne Korwitz-Reichelt, et al https://doi.org/10.1002/jimd.70119

People in this episode

Guest: Jörn Oliver Sass

Topics covered

• D-glyceric aciduria
• mitochondrial localization
• D-glycerate kinase
• biological questions
• fundamentals in biology

Keywords

• D-glyceric aciduria
• GLYCTK
• mitochondrial enzyme
• D-glycerate kinase
• biological fundamentals

Mentioned in this episode

Organizations: Journal of Inherited Metabolic Disease, GLYCTK

Books & works: Human D-Glycerate Kinase, Encoded by GLYCTK and Deficient in D-Glyceric Aciduria, Is a Mitochondrial Enzyme

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