Inside Sionna’s Bid To Normalize CFTR Function

Inside Sionna’s Bid To Normalize CFTR Function

From Lab to Lives by Ivanna Rosendal

December 17, 2025 · 31 min · Season 7 · Episode 7

About this episode

Two leaders from Sionna Therapeutics discuss their journey in advancing therapies for cystic fibrosis.

Send us Fan Mail Two leaders from Sionna Therapeutics walk through a 15‑year journey from Genzyme science to a public company advancing NBD1‑targeted therapies in cystic fibrosis. We examine why most patients still fall short of normal CFTR, how a predictive assay de‑risks choices, and what it takes to finance, hire, and execute with patients as the North Star. Visit: sionnatx.com Visit Labtolives.com Do you want to try the quiz from this episode? Find the link on our LinkedIn profile: h...

People in this episode

Host: Ivanna Rosendal

Guest: two leaders from Sionna Therapeutics

Topics covered

  • cystic fibrosis
  • therapies
  • healthcare
  • biotechnology
  • patient care

Keywords

  • cystic fibrosis
  • CFTR function
  • NBD1-targeted therapies
  • predictive assay
  • patient care

Mentioned in this episode

Organizations: Sionna Therapeutics, Genzyme, sionnatx.com, Labtolives.com

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