What Your Gut Is Telling You About Parkinson's Disease — 20 Years Before Diagnosis

What Your Gut Is Telling You About Parkinson's Disease — 20 Years Before Diagnosis

From Love & Guts by Lynda Griparic | Integrative Practitioner |Gut | Digestion | Constipation |

March 18, 2026 · 59 min

About this episode

This episode explores the connection between gut health and Parkinson's disease, highlighting early warning signs and research insights.

#314 What if chronic constipation, gut dysbiosis, and microbial imbalance were early warning signs of Parkinson's disease — appearing up to 20 years before a diagnosis? In this episode, I sit down with microbiome researcher and founder of The BioCollective, Martha Carlin , whose journey into Parkinson's research began when her husband John was diagnosed at just 44 years old. Martha spent over two decades studying the gut-brain connection in Parkinson's, building one of the first independent IRB-approved human microbiome research initiatives in the world. In this episode, you'll discover: Why chronic constipation can precede a Parkinson's diagnosis by 20+ years — and why it is never normal The two phenotypes of Parkinson's disease and how gut bacteria can distinguish between them The role of hydrogen sulphide, LPS endotoxins, and leaky gut in Parkinson's pathology The mycobacteria connection to Parkinson's that almost nobody is talking about How glyphosate is decimating the good bacteria we need most The glycocalyx — what it is, why it matters, and how to restore it The overlooked cardiovascular risks in Parkinson's disease. Where to start if you or someone you love has just…

People in this episode

Host: Lynda Griparic

Guest: Martha Carlin

Topics covered

  • Parkinson's disease
  • gut health
  • microbiome
  • chronic constipation
  • gut-brain connection
  • health risks

Keywords

  • Parkinson's disease
  • gut dysbiosis
  • chronic constipation
  • microbial imbalance
  • gut-brain connection
  • hydrogen sulphide
  • LPS endotoxins
  • leaky gut
  • mycobacteria
  • glyphosate

Mentioned in this episode

Organizations: The BioCollective

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