
Ep. 26: Can't Sleep, Won't Sleep
From M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder by M4 Podcast
March 18, 2026 · 59 min · Episode 26
About this episode
This episode explores Fatal Familial Insomnia, a rare condition that prevents individuals from sleeping, delving into its implications and the medical community's ongoing search for answers.
Sleep is something we all take for granted until it’s gone. In this episode of Medicine, Mystery, Mayhem & Murder , Andrea and Crystal explore one of the rarest and most terrifying conditions known to medicine: Fatal Familial Insomnia. Imagine a disease where your body simply forgets how to sleep, and no amount of medication, exhaustion, or intervention can bring it back. This is a story about more than just sleep. It is about what happens when one of the most basic human functions is stripped away, and how medicine continues to chase answers in the face of something it still does not fully understand. So get comfortable… and maybe do not listen right before bed.
People in this episode
Hosts: Andrea, Crystal
Topics covered
- sleep disorders
- Fatal Familial Insomnia
- medical mystery
- human functions
- healthcare challenges
Keywords
- sleep
- insomnia
- Fatal Familial Insomnia
- medical mystery
- health
- human functions
- disease
Mentioned in this episode
Books & works: Fatal Familial Insomnia
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