
M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder
by M4 Podcast
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On the show
From 15 epsHosts
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Recent episodes
Ep. 40: Bad Blood
Jun 24, 2026
Unknown duration
EP. 39: Pour Some Sugar on Me
Jun 17, 2026
Unknown duration
Ep. 38: It's Your Poison Running Through My Veins
Jun 10, 2026
1h 11m 27s
Ep. 37: Twist and Shout
Jun 3, 2026
1h 04m 46s
Ep. 36: The Roof, The Roof, The Roof is On Fire
May 26, 2026
58m 31s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 6/24/26 | ![]() Ep. 40: Bad Blood | For forty years, the U.S. government promised free healthcare to a group of men who needed it most. What they delivered instead was decades of deliberate, documented deception. This week, Andrea and Crystal break down the U.S. Public Health Service Syphilis Study at Tuskegee: how it started, why it kept going long after a cure existed, and the nurse caught in the middle of it all. We trace the men behind the headlines, the whistleblower who finally ended it, and the bioethics rules that exist today because of what happened to them. It's a hard one. It's also one of the most important episodes we've made.** Please note, we are aware that Crystal mispronounces "Tuskegee" throughout this episode - our sincerest apologies ** | — | ||||||
| 6/17/26 | ![]() EP. 39: Pour Some Sugar on Me | On January 15, 1919, a massive steel tank in Boston's North End ruptured without warning, releasing 2.3 million gallons of molasses in a wave that reached 25 feet high and moved at 35 miles per hour. It crushed buildings, snapped elevated train tracks, and killed 21 people. The cleanup took weeks. The myths have lasted a century.In this episode, Andrea takes us through one of the strangest industrial disasters in American history. Why was that much molasses sitting in a residential neighborhood? What did rescuers face when the wave finally stopped? And how did a flood of sugar end up changing corporate accountability in America forever?Join Andrea and Crystal as they wade through the science of why this wave was anything but slow, and the medical realities of drowning in syrup. | — | ||||||
| 6/10/26 | ![]() Ep. 38: It's Your Poison Running Through My Veins✨ | Radium Girlstoxic exposure+3 | — | NIH/PMCNIST Journal of Research+2 | New JerseyOttawa, Illinois | Radium Girlspoisoning+3 | — | 1h 11m 27s | |
| 6/3/26 | ![]() Ep. 37: Twist and Shout✨ | Marfan Syndromegenetic disorders+3 | — | fibrillin-1M4 Podcast | — | Marfan Syndromegenetic mutation+4 | — | 1h 04m 46s | |
| 5/26/26 | ![]() Ep. 36: The Roof, The Roof, The Roof is On Fire✨ | Cleveland Clinic Firehospital safety+3 | Crystal | Cleveland Clinic | — | Cleveland Clinicfire+5 | — | 58m 31s | |
| 5/19/26 | ![]() Ep. 35: Wake Up✨ | sleeping sicknessencephalitis lethargica+4 | Andrea | encephalitis lethargica | — | sleeping sicknessencephalitis lethargica+6 | — | 49m 46s | |
| 5/13/26 | ![]() Ep. 34: I Will Survive✨ | survival storiesextraordinary circumstances+4 | — | — | Peruvian AmazonNigerian+2 | survivalJuliane Koepcke+5 | — | 1h 14m 31s | |
| 5/6/26 | ![]() Ep. 33: Get Out, Right Now✨ | psychiatric deinstitutionalizationmental health system+4 | — | Los Angeles County JailRikers Island+2 | — | mental illnessstate psychiatric hospitals+6 | — | 1h 05m 34s | |
| 4/29/26 | ![]() Ep. 32: You Are Not Alone✨ | Third Man Syndromesurvival psychology+5 | — | — | AntarcticaEverest | Third Man Syndromesurvival psychology+8 | — | 1h 02m 20s | |
| 4/22/26 | ![]() Ep. 31: She's So High✨ | opioid epidemicpublic health crisis+4 | Andrea | OxyContinfentanyl+1 | — | opioid epidemicPurdue Pharma+5 | — | 59m 15s | |
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| 4/15/26 | ![]() Ep. 30: I Need a Hero?✨ | true crimemedical malpractice+4 | — | M4 Podcast | — | Niels Högelnurse+6 | — | 1h 00m 23s | |
| 4/8/26 | ![]() Ep. 29: Breathe In, Breathe Out✨ | COVID-19respiratory illness+4 | Andrea | Medicine, Mystery, Mayhem & Murder | Wuhan, China | COVID-19respiratory illness+4 | — | 55m 58s | |
| 4/1/26 | ![]() Ep. 28: Paralyzer✨ | paralysischannelopathies+4 | Crystal | Periodic Paralysis | — | Periodic Paralysisparalysis+4 | — | 1h 27m 55s | |
| 3/25/26 | ![]() Ep. 27: Mama, Just Killed A Man✨ | murdertrue crime+4 | — | — | UtahSalt Lake City+1 | murderFranklin Bradshaw+4 | — | 44m 08s | |
| 3/18/26 | ![]() Ep. 26: Can't Sleep, Won't Sleep✨ | sleep disordersFatal Familial Insomnia+3 | — | Fatal Familial Insomnia | — | sleepinsomnia+5 | — | 58m 58s | |
| 3/11/26 | ![]() Ep. 25: Down in a Hole✨ | rescue operationBaby Jessica+4 | — | — | Midland, Texas | Baby Jessicarescue+5 | — | 49m 50s | |
| 3/4/26 | ![]() Ep. 24: I am Iron Man✨ | iron lungpolio+4 | — | iron lung | — | iron lungpolio+5 | — | 1h 28m 10s | |
| 2/25/26 | ![]() Ep. 23: Doctor, Doctor | In 1999, Dr. Jerri Nielsen was the only physician stationed at the South Pole when she discovered a lump in her breast — after the last plane had already left. With evacuation impossible, she diagnosed, biopsied, and began treating her own cancer while trapped in one of the most isolated places on Earth.This episode explores her story alongside other moments when medicine had to happen without rescue: self-surgery in Antarctica, healthcare in disaster zones, and the realities of telemedicine when infrastructure disappears.Andrea and Crystal examine what happens when the provider becomes the patient, how isolation changes decision-making, and what these stories reveal about resilience, preparedness, and the human side of care.Because sometimes survival begins long before help arrives. | — | ||||||
| 2/18/26 | ![]() Ep. 22: No One Knows What it's Like - Michael Swango Pt 2 | In Part Two of our deep dive into Michael Swango, we follow the trail all the way to the end — the arrests, the lies, the international flight, and the staggering body count that may never be fully known.How did he continue practicing medicine after convictions? How did hospitals miss — or ignore — the warnings? And how many patients paid the price for institutional silence and fragmented reporting systems?We walk through the criminal charges, the federal case, and the ultimate sentence that finally stopped him. We also talk about what changed in healthcare because of him, and where the gaps still remain.This isn’t just the story of one man.It’s a story about systems that failed.About oversight that came too late.And about the uncomfortable truth that sometimes the white coat hides more than it heals.If you thought Part One was disturbing… this is where it all comes into focus. | — | ||||||
| 2/11/26 | ![]() Ep. 21: No One Knows What It’s Like | He wore scrubs. He took an oath. And somehow, he kept getting hired.In Part One of our two-part series, we unravel the early life and chilling rise of one of healthcare’s most unsettling figures: Michael Swango.From his time as a paramedic to medical school to his first hospital positions, red flags followed him everywhere — mysterious patient deaths, co-workers collapsing after shared meals, and stories that just didn’t add up. And yet, again and again, he slipped through the cracks.How does someone with repeated allegations, suspicious patterns, and documented concerns continue practicing medicine? Was it arrogance? Manipulation? System failure? Or something far more disturbing?This week, we focus on the making of a monster — the warning signs, the overlooked victims, and the institutional blind spots that allowed him to keep moving forward.Because sometimes the most terrifying part of the story isn’t just what one person did…It’s who let him. | — | ||||||
| 2/4/26 | ![]() Ep. 20: Remember When | Some kids know things they were never taught.They use words too old for their mouths.They recognize places they’ve never been.They speak with a certainty that makes adults stop and stare.In this episode, Andrea and Crystal explore stories of children who seem to know more than their age should allow—history, skills, details, and memories that feel unsettling, fascinating, and deeply human. Are these coincidences? Exceptional intelligence? Something stranger? Or a reminder that we don’t fully understand how knowledge, memory, and identity really work?We’ll share compelling cases, thoughtful questions, and just enough wonder to leave you thinking long after the episode ends. Perfect for listeners who enjoy mystery without fear, curiosity without cynicism, and stories that gently tug at the edges of what we think we know.Sources:Stevenson, I. Children Who Remember Previous LivesStevenson, I. Where Reincarnation and Biology IntersectTucker, J. Return to LifeUniversity of Virginia – Division of Perceptual Studies (peer-reviewed publications)Journal of Consciousness StudiesJournal of Nervous and Mental DiseaseBBC News & BBC Future long-form investigationsSmithsonian Magazine (historical reporting) | — | ||||||
| 1/28/26 | ![]() Ep. 19: If You Believe in Miracles | Sometimes you don’t need answers—you just need a breather.This shorter-than-usual episode of Medicine, Mystery, Mayhem & Murder is a palate cleanser for heavy times, focused on miracle survival stories that had no business ending well… but somehow did. Catastrophic injuries, medical long shots, impossible timing—and the stubborn refusal of the human body to give up.There’s no cruelty and no villains here. Just resilience, luck, and moments that make you stop and say, okay, maybe the universe isn’t done with us yet. Consider this a deep breath, a spark of awe, and a reminder that survival itself can still feel miraculous. | — | ||||||
| 1/21/26 | ![]() Ep. 18: Sending Out an SOS | Sometimes the universe whispers instead of shouts. A stranger pays a bill at just the right moment. Help appears when no one knew to ask. A door opens when every other one has slammed shut. In this episode, Andrea and Crystal explore unexplained small miracles and random acts of kindness that arrive without warning and leave people forever changed. Coincidence, compassion, or something more? You decide. But these stories might just restore your faith in humanity. | — | ||||||
| 1/14/26 | ![]() Ep. 17: Memories | Did Nelson Mandela really die in prison? Was it Berenstain or Berenstein Bears? And why do so many of us remember the exact same things… wrong?In this episode, Andrea and Crystal unravel the Mandela Effect, the bizarre phenomenon where collective memories don’t line up with reality. We dig into the most famous examples, why our brains might be gaslighting us, and the theories that range from psychology and social influence to parallel timelines and simulation glitches.Is this just how memory works, or is something else going on? Either way, once you notice it, you can’t unsee it. | — | ||||||
| 1/7/26 | ![]() Ep. 16: Disappear | Some disappearances are mysterious.Others are tragic.A rare few feel like they break the rules of reality itself.In this episode of Medicine, Mystery, Mayhem & Murder (M⁴), Andrea and Crystal explore seven cases where people didn’t just go missing — they seemed to vanish in ways that shouldn’t be physically possible. | — | ||||||
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