Understanding Obesity Phenotypes

Understanding Obesity Phenotypes

From Mayo Clinic on Nutrition by Mayo Clinic Press

April 21, 2026 · 38 min

About this episode

This episode explores the concept of obesity phenotypes and how they influence weight loss strategies.

Why do some people seem to shed weight easily while others don’t get the same results, no matter how hard they try? According to the theory of obesity phenotypes, the way each of us gains weight is different — and the best way to lose it may be different, too. On this episode of On Nutrition, bariatrician, gastroenterologist and internist Dr. Andres Acosta shares his research on obesity phenotypes, how genetics can play a role in developing obesity, and how a person’s phenotype gives providers a pathway to tailor treatment. Sign up⁠ to receive Mayo Clinic Press emails. Find us online at ⁠Mayo Clinic Press⁠ for more health and wellness articles, podcasts and books. Do you have feedback, questions or topic suggestions? Email us at ⁠mcppodcasts@mayo.edu⁠.

People in this episode

Guest: Dr. Andres Acosta

Topics covered

  • obesity
  • weight loss
  • genetics
  • healthcare
  • treatment

Keywords

  • obesity phenotypes
  • weight loss
  • genetics
  • bariatrician
  • health

Mentioned in this episode

Organizations: Mayo Clinic Press

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