First Keto Trial for Anorexia Nervosa: 72% Showed Recovery

First Keto Trial for Anorexia Nervosa: 72% Showed Recovery

June 3, 2026 · 4 min

About this episode

Dr. Guido Frank discusses the first clinical trial of ketogenic therapy for individuals with weight-normalized anorexia nervosa, highlighting significant recovery rates.

A new study demonstrates that ketogenic therapy could be an option for individuals living with weight-normalized anorexia nervosa. One of the primary goals of anorexia nervosa treatment is restoring weight, and while this is an important milestone, many individuals continue to experience psychological symptoms. Dr. Guido Frank, Professor of Psychiatry at UC San Diego, has spent more than 25 years researching and treating eating disorders. For much of his career, the lack of effective biological treatments for anorexia nervosa has been one of his greatest frustrations. That changed when he began investigating ketogenic therapy. In this video, Dr. Frank shares results from the first-ever clinical trial of ketogenic therapy in anorexia nervosa, published in Communications Medicine . This 14-week outpatient feasibility trial enrolled adults living with weight-normalized anorexia nervosa who, despite weight restoration, continued to struggle with persistent eating disorder symptoms. Of the 22 individuals enrolled in the study, 82% completed the trial. Among those who completed, 40% experienced mild early side effects, all of which resolved by study end, providing early evidence that…

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