Reversing & Preventing Fatty Liver with Metabolic Therapies | Dr. Adam Wolfberg

Reversing & Preventing Fatty Liver with Metabolic Therapies | Dr. Adam Wolfberg

From Metabolic Mind by Bret Scher

May 18, 2026 · 28 min

About this episode

Dr. Bret Scher interviews Dr. Adam Wolfberg about reversing and preventing fatty liver disease through metabolic therapies.

Fatty liver disease (MASLD) is a major cause of liver disease and even liver failure. But many are surprised to learn it’s not primarily a liver problem. Growing evidence suggests the root issue may be metabolic dysfunction affecting the entire body, and that perspective can drastically change how we approach treating and preventing it. In this interview, Dr. Bret Scher sits down with Dr. Adam Wolfberg to discuss a newly published study in Hepatology examining how a ketogenic intervention may help prevent metabolic liver disease before it progresses. The conversation explores MASLD (metabolic dysfunction-associated steatotic liver disease) and MASH (metabolic dysfunction-associated steatohepatitis), conditions that now affect millions of people and are closely linked to obesity, insulin resistance, and type 2 diabetes. You’ll learn: Why metabolic diseases are deeply interconnected How ketogenic interventions may improve liver health What the new research found about preventing MASLD and MASH Why weight loss alone may not explain the benefits How lifestyle interventions compare to pharmaceutical approaches Why prevention is often overlooked in modern healthcare The broader…

People in this episode

Host: Bret Scher

Guest: Adam Wolfberg

Topics covered

  • fatty liver disease
  • metabolic dysfunction
  • ketogenic intervention
  • liver health
  • chronic disease prevention

Keywords

  • fatty liver disease
  • metabolic dysfunction
  • ketogenic diet
  • MASH
  • MASLD
  • insulin resistance
  • chronic disease

Mentioned in this episode

Organizations: Hepatology

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