How Weight Loss Medications Actually Work in Your Body
From Mindfully Integrative Show by Dr. Damaris Grossmann FNP-C
February 20, 2026 · 7 min
About this episode
This episode explains how GLP-1 receptor agonists work in the body to regulate appetite and metabolism.
Send us Fan Mail We break down the mechanism of action for GLP-1 receptor agonists like tirzepatide (Zepbound/Mounjaro) and semaglutide, explaining how these medications work in the body to regulate appetite and metabolism. • GLP-1 medications contain a C20 fatty diacid that binds to albumin, prolonging half-life • These drugs target both GIP and GLP-1 receptors to regulate appetite and caloric intake • Receptors are found in brain areas involved in appetite regulation and throughout the GI ...
People in this episode
Host: Dr. Damaris Grossmann
Topics covered
- weight loss
- medications
- appetite regulation
- metabolism
- health education
Keywords
- weight loss medications
- GLP-1 receptor agonists
- tirzepatide
- semaglutide
- appetite regulation
- metabolism
Mentioned in this episode
Organizations: Zepbound, Mounjaro, GLP-1, GIP
Products: tirzepatide, semaglutide
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