AI’s Next Frontier with Dr. Kyunghyun Cho

About this episode

Dr. Kyunghyun Cho discusses the applications of AI in healthcare and emphasizes the importance of patient voices in AI governance.

Dr. Kyunghyun Cho is a leading AI researcher best known for co-authoring a landmark 2014 paper that introduced neural machine translation. In this episode, he discusses his wide-ranging career spanning fundamental AI research, co-founding Prescient Design (acquired by Genentech), and driving applications of AI in health care. For clinicians, Cho’s core message is pragmatic: AI should help health care run better. After years of work at NYU Langone, he reframed AI in medicine from solving rare diagnostic puzzles to improving operational prediction at scale. Cho emphasizes purpose‑built data, careful fine‑tuning, and regulatory accountability. His perspective connects technical rigor with system stewardship—and insists that patient voices must be present in AI governance. Transcript.

People in this episode

Host: NEJM Group

Guest: Dr. Kyunghyun Cho

Topics covered

• AI in healthcare
• neural machine translation
• operational prediction
• data governance
• AI research

Keywords

• AI
• healthcare
• neural machine translation
• operational prediction
• data governance
• clinical applications

Mentioned in this episode

Organizations: Prescient Design, Genentech, NYU Langone

More episodes of NEJM AI Grand Rounds

• The OpenEvidence Episode: Dr. Travis Zack on the Future of Clinical Evidence · May 20, 2026 · 1h 6m
• Doctronic’s Autonomous AI with Dr. Byron Crowe · April 15, 2026 · 51 min
• Epic’s Approach to AI with Seth Hain · February 18, 2026 · 53 min
• Bridging AI and Biology to Tackle Medicine’s Hardest Problems with Dr. Marinka Zitnik · January 21, 2026 · 54 min
• What Values are in AI? A Conversation with Dr. Zak Kohane · December 17, 2025 · 1h 18m
• From Hindsight Bias to Machine Bias: Dr. Laura Zwaan on Learning from Mistakes · November 19, 2025 · 38 min