
Epic’s Approach to AI with Seth Hain
From NEJM AI Grand Rounds by NEJM Group
February 18, 2026 · 53 min · Episode 39
About this episode
Seth Hain discusses Epic's approach to building AI models that prioritize safety and trust in clinical settings.
Clinical AI only helps patients if clinicians and health systems trust it. Seth Hain describes how Epic is building foundation models that respect institutional autonomy, minimize burden, and prioritize safety. He discusses scaling laws in structured medical data, cautious deployment for clinical interventions, and why understanding causality—not just correlation—is essential. This conversation reframes AI not as disruption, but as infrastructure for safer, more reliable care. Transcript.
People in this episode
Guest: Seth Hain
Topics covered
- AI in healthcare
- clinical interventions
- trust in AI
- medical data
- safety in AI
- causality vs correlation
Keywords
- AI
- healthcare
- Epic
- clinical data
- safety
- trust
- causality
- correlation
Mentioned in this episode
Organizations: Epic, NEJM Group
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