Epic’s Approach to AI with Seth Hain

Epic’s Approach to AI with Seth Hain

From NEJM AI Grand Rounds by NEJM Group

February 18, 2026 · 53 min · Episode 39

About this episode

Seth Hain discusses Epic's approach to building AI models that prioritize safety and trust in clinical settings.

Clinical AI only helps patients if clinicians and health systems trust it. Seth Hain describes how Epic is building foundation models that respect institutional autonomy, minimize burden, and prioritize safety. He discusses scaling laws in structured medical data, cautious deployment for clinical interventions, and why understanding causality—not just correlation—is essential. This conversation reframes AI not as disruption, but as infrastructure for safer, more reliable care. Transcript.

People in this episode

Guest: Seth Hain

Topics covered

  • AI in healthcare
  • clinical interventions
  • trust in AI
  • medical data
  • safety in AI
  • causality vs correlation

Keywords

  • AI
  • healthcare
  • Epic
  • clinical data
  • safety
  • trust
  • causality
  • correlation

Mentioned in this episode

Organizations: Epic, NEJM Group

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