Big News From ESMO 2025 Changes Practice in Bladder Cancer

About this episode

The episode discusses significant findings from the ESMO 2025 that are set to change the standard of care for muscle-invasive bladder cancer.

Survival data from the KEYNOTE-905 trial and insights into the use of circulating tumor DNA to guide treatment decisions from IMvigor011 made big waves in bladder cancer care at the European Society of Medical Oncology Annual Congress. “Overall, this is going to change the standard of care for muscle-invasive bladder cancer,” says Amanda Nizam, MD, a genitourinary medical oncologist at the Cleveland Clinic Taussig Cancer Institute. She and Robert A. Figlin, MD, the interim director of Cedars-Sinai Cancer in Los Angeles and Steven Spielberg Family Chair in Hematology-Oncology, discuss how the findings are being incorporated into clinic and what questions remain. “I am continually surprised by the changes taking place in bladder cancer management,” notes Dr. Figlin. Dr. Nizam reported various financial relationships. Dr. Figlin reported various financial relationships.

People in this episode

Guests: Amanda Nizam, MD, Robert A. Figlin, MD

Topics covered

• bladder cancer
• oncology
• clinical trials
• treatment decisions
• standard of care

Keywords

• bladder cancer
• KEYNOTE-905
• IMvigor011
• treatment decisions
• survival data
• oncology
• ESMO 2025

Mentioned in this episode

Organizations: Cleveland Clinic Taussig Cancer Institute, Cedars-Sinai Cancer, KEYNOTE-905, IMvigor011

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