Should Patients With Cancer Receive mRNA Vaccines Alongside Immunotherapy?

Should Patients With Cancer Receive mRNA Vaccines Alongside Immunotherapy?

November 21, 2025 · 13 min · Episode 19

About this episode

The episode discusses the potential benefits of mRNA vaccines in enhancing cancer immunotherapy responses.

A recent study found a link between mRNA vaccination and improved cancer immunotherapy response. The preclinical data demonstrated impressive results, leading to big questions. “We believe that [vaccination] actually does generate and even converts the cold tumors to hot tumors,” Steven H. Lin, MD, PhD, a physician-scientist and radiation oncologist at the University of Texas MD Anderson Cancer Center in Houston, tells Robert A. Figlin, MD, the interim director of Cedars-Sinai Cancer Center in Los Angeles and Steven Spielberg Family Chair in Hematology-Oncology.

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