Breaking Free From Depression

Breaking Free From Depression

August 6, 2026 · 54 min · Episode 155

About this episode

This episode discusses the clinical nature of depression and its impact on brain function with expert insights from Dr. James Murrough.

Depression is often mistaken for ordinary sadness, but clinically it is something profoundly different: a medical illness that can alter the way the brain processes emotion, motivation, and even hope itself. In this episode of Road to Resilience, host Stephen Calabria speaks with James Murrough, MD, PhD, to discuss how groundbreaking neuroimaging research explains why depression may leave the brain "entrapped" in inefficient patterns of activity, The conversation explores the difference...

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