GLP-1s and Muscle Loss: What Ozempic Users Need to Know

About this episode

This episode discusses the impact of GLP-1 medications on muscle loss and offers practical steps to preserve muscle health.

One in eight American adults have now tried a GLP-1 (Ozempic, Wegovy, Mounjaro, Zepbound). The drugs work—people lose 15-22% of their body weight in clinical trials. But new research published this month confirms what many suspected: 25-40% of that weight loss is muscle, not fat. That is catastrophic for long-term metabolic health, strength, and healthspan. This episode breaks down the latest meta-analysis, explains why muscle loss matters (it's not just vanity—muscle is your metabolic engine, structural support, and predictor of longevity), and offers five practical steps to preserve muscle if you're on or considering GLP-1s. If you're considering GLP-1s, on them currently, or have an aging parent using them—this is the conversation you need to hear. PLUS THIS WEEK'S HEALTH & FITNESS NEWS - Mayo Clinic’s AI detects pancreatic cancer up to 3 years before clinical diagnosis - Tick bite surge — early-season Lyme disease risk hits the Northeast - The simple at-home strength test JAMA Network Open just linked to longevity - The exact daily step count that prevents weight regain after dieting - GLP-1 muscle loss — the biggest health and fitness story of the week SPONSORS/PRODUCTS…

People in this episode

Host: Altum Fitness

Topics covered

• GLP-1 medications
• muscle loss
• weight loss
• metabolic health
• longevity
• health news

Keywords

• Ozempic
• muscle loss
• weight loss
• metabolic health
• longevity
• GLP-1
• health news

Sponsors

Purist Nutrition, Based Body Works

Mentioned in this episode

Organizations: Ozempic, Wegovy, Mounjaro, Zepbound, Mayo Clinic, JAMA Network Open

Products: GLP-1s

Places: Northeast

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