A PSA on TXA: Updated recommendations for TXA in Trauma

A PSA on TXA: Updated recommendations for TXA in Trauma

From TamingtheSRU by UC Department of Emergency Medicine

November 23, 2025 · 14 min

About this episode

Dr. Segev reviews key TXA trials and highlights updated guidelines for its use in trauma care.

Tranexamic acid (TXA) is an anti-fibrinolytic that may reduce hemorrhage and improve survival in trauma. While early studies raised safety concerns, newer evidence supports its use in select patients. Join Dr. Segev as he reviews key TXA trials and highlights the updated EAST guidelines on pre-hospital and in-hospital administration.

People in this episode

Guest: Dr. Segev

Topics covered

  • TXA
  • trauma
  • hemorrhage
  • survival
  • EAST guidelines
  • pre-hospital care
  • in-hospital administration

Keywords

  • TXA
  • tranexamic acid
  • trauma
  • hemorrhage
  • EAST guidelines
  • pre-hospital administration
  • in-hospital administration

Mentioned in this episode

Organizations: EAST

Products: Tranexamic acid (TXA)

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