Two‑Bag Triumph? What the Evidence Really Shows in Diabetic Ketoacidosis Care
From TamingtheSRU by UC Department of Emergency Medicine
May 23, 2026 · 4 min
About this episode
This episode discusses the evidence surrounding fluid management strategies in diabetic ketoacidosis care.
Diabetic ketoacidosis is a familiar ED diagnosis, but the best fluid strategy is still up for debate. Many of us default to the traditional one‑bag system, even though it can be slow to adjust and prone to glucose swings. This new meta‑analysis compares one‑bag versus two‑bag DKA management across adults and children, examining hypoglycemia rates, time to resolution, and operational impact. Join Dr. Knudsen-Robbins as she breaks down what the evidence shows — and whether the two‑bag fluid system truly offers a clinical edge for treatment.
People in this episode
Host: Dr. Knudsen-Robbins
Topics covered
- diabetic ketoacidosis
- fluid management
- meta-analysis
- emergency medicine
- clinical care
Keywords
- diabetic ketoacidosis
- fluid strategy
- one-bag system
- two-bag system
- hypoglycemia rates
- time to resolution
- emergency department
Mentioned in this episode
Organizations: UC Department of Emergency Medicine
Books & works: Diabetic Ketoacidosis
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