Clinical Confidence: Off-Label Prescribing Done Right with Leigh Ann Pansch
About this episode
Leigh Ann Pansch discusses the importance of off-label prescribing in dermatology and shares insights on clinical decision-making and patient care.
Off-label prescribing is one of the most valuable—and often misunderstood—tools in dermatology. In this episode of That's Derm Good! , Leigh Ann Pansch shares how thoughtful clinical reasoning, thorough documentation, and collaborative care can open new treatment opportunities for patients when standard options aren't enough. Leigh Ann reflects on her journey from nursing into dermatology, discussing how mentorship, fellowship training, and a commitment to lifelong learning shaped her career. She explains why dermatology providers frequently prescribe medications beyond their FDA-approved indications and how these decisions are grounded in scientific evidence, clinical experience, and individualized patient care. The conversation also explores the evolving relationship between providers, biologic coordinators, insurance companies, and pharmaceutical manufacturers. Leigh Ann offers practical advice on documenting medical necessity, communicating quality-of-life impacts, and navigating insurance approvals for both labeled and off-label therapies. Through real patient stories—including pediatric dermatology and alopecia cases—she demonstrates how collaboration across the healthcare…
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