The Dr. Ardis Show | Top 20 Drugs: Acid Reflux | Episode 06.10.2026

The Dr. Ardis Show | Top 20 Drugs: Acid Reflux | Episode 06.10.2026

From The Dr. Ardis Show Podcast by Dr Bryan Ardis

June 10, 2026 · 51 min

About this episode

Dr. Bryan Ardis discusses the top drugs for acid reflux and presents natural alternatives backed by research.

Antacids and heartburn medications are the most-purchased over-the-counter category in America and two of them rank among the top 20 most prescribed prescription drugs of 2025: Omeprazole (Prilosec, Prilosec OTC) at #7 and Pantoprazole (Protonix) at #15. Both are proton pump inhibitors (PPIs). In this episode, Dr. Bryan Ardis walks through the FDA-published side effect profiles of these PPIs. Then he lays out the natural, research-backed alternatives that soothe, protect, and restore normal digestion - without suppressing the stomach acid your body needs. Nature Wins Magnesium Complex - magnesium relaxes the pyloric sphincter and improves gastric emptying, lowering pressure on the lower esophageal sphincter; supplementation shown to improve reflux and GERD symptoms. Nature Wins Zinc Plus - zinc reduces gastric acid secretion as effectively as PPIs without the side effects; zinc paired with L-carnitine shown to repair and protect the GI mucosa. Nature Wins Hydrate Complete - delivers vitamins A, C, E, B6, B9, and B12, plus magnesium, zinc, L-arginine, glycine, and betaine, the antioxidants and amino acids tied in studies to lower reflux, Barrett's esophagus, and esophageal cancer…

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