AMA 04 - Cortisol, Seed Oils, Insulin, Biggest Loser and More

About this episode

Layne Norton answers listener questions on various topics related to training, nutrition, and practical science.

In this listener Q&A, Layne dives deep into your most-asked questions on training, nutrition, and practical science. As always, he breaks down the actual research and gives no-BS, evidence-based takeaways you can actually use. Topics covered in this episode: • Does cortisol cause fat gain? Plus the impact of low-calorie dieting on cortisol • Sucralose and gut health – new research on dysbiosis, glucose/insulin levels, and the role of Blautia • Do seed oils increase inflammation? Comprehensive look at linoleic acid studies, systematic reviews, and clinical trials • Insulin, high-glycemic carbs, and fat storage – what do overfeeding studies actually show? • Is “natural” always better? The naturalistic fallacy explained • Is resistance training safe and effective for kids? What the science says for youth training • Creatine dosing for women vs. men – do women need a different amount? • Does cardio interfere with building muscle? Latest meta-analyses on concurrent training • Layne’s honest take on The Biggest Loser Netflix documentary • And more! Whether you’re chasing muscle gains, fat loss, or just cutting through the noise, this episode delivers the science-backed answers…

People in this episode

Host: Layne Norton

Topics covered

• cortisol and fat gain
• seed oils and inflammation
• insulin and fat storage
• youth resistance training
• creatine dosing
• cardio and muscle building
• The Biggest Loser documentary

Keywords

• cortisol
• seed oils
• insulin
• resistance training
• creatine
• cardio
• The Biggest Loser
• nutrition
• fat gain
• evidence-based

Sponsors

REPS, Workout Builder

Mentioned in this episode

Organizations: The Biggest Loser, Carbon Diet Coach, Outwork Nutrition

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• Blood Flow Restriction Training with Jeremy Loenneke · April 13, 2026 · 2h 19m
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