Study Deep Dive: Does Aspartame Increase Insulin?

About this episode

Layne Norton dissects a systematic review on the effects of aspartame on insulin and glucose responses.

In this episode, Layne Norton, PhD, dissects the landmark 2025 systematic review & meta-analysis in Advances in Nutrition: "The Effects of Aspartame on Glucose, Insulin, and Appetite-Regulating Hormone Responses in Humans". (PMID: 40381807) This episode is perfect if you've heard claims like "diet soda spikes insulin," "artificial sweeteners cause diabetes," or "aspartame is toxic" — Layne uses this gold-standard review to separate science from fear-mongering. If you're into evidence-based nutrition, skeptical of viral health scares, or just want to know if your Diet Coke habit is secretly wrecking your metabolism — this episode has the receipts. Subscribe for more deep-dive breakdowns of the latest research, and drop a comment: Do you use aspartame? Has this changed your view? SPONSORS • Outwork Nutrition - Evidence-Based Supplements to Support Your Hard Work: https://outworknutrition.com • David Protein - Buy 4 cartons, get 1 FREE at: https://davidprotein.com/pages/layne LAYNE'S COMPANIES Carbon Diet Coach: https://joincarbon.com/podcast Outwork Nutrition: https://outworknutrition.com REPS Research Review: https://biolayne.com/reps Workout Builder…

People in this episode

Host: Layne Norton

Topics covered

• aspartame
• insulin
• diet soda
• nutrition research
• health claims
• metabolism

Keywords

• aspartame
• insulin
• diet soda
• artificial sweeteners
• nutrition
• meta-analysis
• health claims

Sponsors

Outwork Nutrition, David Protein

Mentioned in this episode

Organizations: Advances in Nutrition, Carbon Diet Coach, REPS Research Review, Workout Builder, Team Biolayne, Physique Coaching Academy

Products: Evidence-Based Supplements

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