Fenebrutinib in Relapsing MS: FENhance Trial Results Explained
From The ECTRIMS Podcast by The European Committee for Treatment and Research in Multiple Sclerosis
April 22, 2026 · 26 min
About this episode
Experts discuss the FENhance trial results for fenebrutinib as a treatment for relapsing MS.
New Phase 3 data presented at the AAN conference 2026 provide compelling evidence that fenebrutinib may represent a high-efficacy oral treatment option for people living with relapsing multiple sclerosis. In this exclusive episode, leading experts Prof. Ludwig Kappos from University of Basel and Dr. Jiwon Oh from Barlo MS Centre join host Brett Drummond to unpack the full FENhance 1 & 2 trial results. Together, they explore: How fenebrutinib performed against teriflunomide in relapsing MS Why BTK inhibition continues to generate strong interest across the MS treatment landscape What the results reveal about relapse reduction, MRI outcomes, and disability progression What the safety profile of fenebrutinib looked like in this cohort of patients Listen for a deep dive into the science, clinical context, and future implications for MS care.
People in this episode
Host: Brett Drummond
Guests: Prof. Ludwig Kappos, Dr. Jiwon Oh
Topics covered
- relapsing multiple sclerosis
- fenebrutinib
- clinical trials
- treatment options
- safety profile
- relapse reduction
- MRI outcomes
Keywords
- fenebrutinib
- relapsing MS
- AAN conference
- FENhance trial
- teriflunomide
- BTK inhibition
- disability progression
- MRI outcomes
- safety profile
Mentioned in this episode
Organizations: University of Basel, Barlo MS Centre
Products: fenebrutinib, teriflunomide
Books & works: FENhance 1 & 2 trial results
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