Is ChatGPT Now the World's Largest Health App? | OpenAI VP of Health Nate Gross, MD

Is ChatGPT Now the World's Largest Health App? | OpenAI VP of Health Nate Gross, MD

From The Heart of Healthcare | A Digital Health Podcast by Massively Better Healthcare

April 27, 2026 · 47 min · Episode 228

About this episode

The episode discusses the impact of ChatGPT as a health app and features an interview with OpenAI's VP of Health, Nate Gross, MD.

Forty million people use ChatGPT for health-related questions every day, making it one of the most widely used tools for health information in the world . So what is their team doing to maximize impact and minimize harm? For one, they've brought in hundreds of physicians globally to continuously review outputs and shape how the models respond across different scenarios, literacy levels, and edge cases. Second, they've hired my Rock Health co-founder, Nate Gross, MD, as their VP of Health. In this full-circle episode, I sit down with Nate, who also co-founded Doximity (DOCS) and knows a thing or two about building in digital health. We discuss the astonishing speed of AI progress, how models are trained for safety and accuracy, and what this technological evolution means for every part of the healthcare system. Key topics: How ChatGPT is becoming a 24/7 front door for health questions, and whether it is replacing Dr. Google or starting to compete with the healthcare system itself How OpenAI is trying to reduce hallucinations, avoid sycophantic behavior, and build guardrails for sensitive use cases like mental health OpenAI’s goals to “raise the floor, sweep the floor, and raise…

People in this episode

Guest: Nate Gross, MD

Topics covered

Keywords

Mentioned in this episode

Organizations: OpenAI, Doximity, Rock Health

Products: ChatGPT, ChatGPT for Clinicians, GPT-Rosalind

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