About this episode

Kris Gethin explores the science and implications of Tesamorelin in targeting visceral fat and promoting health span.

Discover the science behind Tesamorelin, a research peptide targeting visceral fat and promoting health span. Kris Gethin breaks down its mechanisms, research findings, and implications for fat distribution and longevity. Tesamorelin is a synthetic analog of growth hormone release hormone (GHRH), stimulating the pituitary to release endogenous growth hormone rather than supplying synthetic GH. It primarily targets deep visceral fat, especially around organs, instead of just superficial subcutaneous fat. Visceral fat is linked to metabolic diseases, inflammation, insulin resistance, and overall aging; reducing it can extend health span. Research shows Tesamorelin reduces visceral fat by approximately 14-18% over 26 weeks without significant weight change. Unlike appetite suppressants like GLP-1 agents, Tesamorelin is considered weight-neutral, aiming for fat redistribution rather than broad weight loss. The effects on body composition include improved fat distribution, preservation of lean mass, and healthier metabolic markers. It can influence glucose tolerance and may cause fluid retention, joint pain, or injection site reactions, especially in older or metabolic-compromised…

People in this episode

Host: Kris Gethin

Topics covered

• Tesamorelin
• fat loss
• health span
• visceral fat
• metabolic health
• growth hormone

Mentioned in this episode

Organizations: GLP-1

Products: Tesamorelin

More episodes of The Kris Gethin Podcast

• 267. Life Update: Getting Sick in India, Social Media Bans, and the Dangers of Unregulated Supplements · July 16, 2026 · 51 min
• 266. The Science Behind Oral Bioregulators for Aging and Performance · July 10, 2026 · 30 min
• 265. The Free Health Habits That Make Biohacking Work · July 2, 2026 · 35 min
• 264. Why Researchers Are Rethinking Tanning: Melanotan Explained · June 25, 2026 · 17 min
• 262. The Food Label Lie: Why Your "Healthy" Food May Not Be What You Think with Will Harris · June 9, 2026 · 1h 1m
• 261. The Peptide Strategy Behind Rapid Tissue Repair · May 29, 2026 · 30 min

Explore listener stats, chart rankings, contacts and more on the The Kris Gethin Podcast podcast page.